Senior Protein Scientist

CV-LibraryMacclesfield, Cheshire EastpermanentPosted: 3 July 2026
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Senior Protein Scientist

Permanent, full-time, onsite.

Location: Macclesfield

Up to c£40,000 depending on experience.

Our client are a multi-national drug discovery organisation providing a range of research services and internal drug discovery programmes across a variety of disease areas and drug modalities. They are currently seeking to expand their protein science team with the addition of a full-time and permanent Senior Scientist.

As a Senior Scientist within the Protein Sciences team, you will be responsible for:

* Supporting and leading client drug discovery projects across biologics and antibody portfolios.

* Designing and running a range of protein biochemistry experiments including protein design (using a range of molecular biology techniques including cloning), protein expression (using AKTA systems for IEX, SEC etc), protein characterisation (using DLS, HPLC, capillary electrophoresis and plate assays).

* Supporting the growth of more junior team members, some of whom will report directly into you. This will include creating personal development plans and other management responsibilities.

* Liaising with clients throughout the projects including data updates, presentations and scope of works.

* Working on multiple projects simultaneously.

To be successful in this position, our client are accepting applications from candidates with the following experience:

* PhD in a biological or biochemical discipline, with additional post-doctoral experience (essential, ideally with industry experience of 1+ year), or a MSc / BSc with 5+ years of industry experience in biochemistry / protein research.

* Prior experience in supervising or managing scientists / technicians (essential)

* Must have strong protein biochemistry knowledge (essential, structural biology and/or biophysical characterisation is a bonus).

* Must have experience in designing proteins using molecular biology (cloning, CRISPR etc) (essential)

* Must have protein expression experience across a range of systems including mammalian and bacterial (essential)

* Must have protein purification and characterisation experience using ion-exclusion chromatography, size-exclusion chromatography, affinity, AKTA / FPLC, plate-based assays, capillary electrophoresis (essential)

* Protein characterisation experience using biophysical (DLS, SPR etc) (desired)

* Experience of liaising with external partners / clients for project updates (desired)

The Package

As an established global organisation, our client is able to offer a competitive salary, progression options and benefits package including private pension

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